We’re seeking highly motivated chemists to join our Chemical Development team at our Upper Providence site, in the suburbs of Philadelphia. As a member of Chemical Development, you will use your chemistry knowledge and expertise to develop new chemistry routes for primary manufacture and contribute to the development and deployment of state-of-the-art processes and technologies to enable the delivery of our medicines.

Chemical Development supports the small molecule portfolio in GSK Pharma R&D and develops the manufacturing routes and processes that turn those molecules into medicines. Through our network of 86 manufacturing sites, each year we produce nearly 4 billion packs of medicine and we are committed to widening access to our products so that more people may benefit. 

Located less than 30 miles from the center of Philadelphia, our R&D hub at Upper Providence, is built on 281 acres of gently rolling land and is home to over 3,000 of our R&D staff. With this concentration of scientists, you will find a culture that inspires innovation, teamwork, and personal development while operating with transparency, respect and integrity.

At GSK we are committed to overcoming some of the biggest challenges in global health; delivering products of value in a responsible, sustainable way; and providing access to medicine for the world's poorest communities.

The environment is highly technical and dynamic as you will be collaborating across multi-disciplinary project teams. You will thrive in this environment if you are able to effectively prioritize and manage multiple tasks, communicate your recommendations clearly, and if you are a team player who enjoys working in diverse teams. 

Yours is a practical role where you will combine the information generated in laboratory studies with your strong knowledge of synthetic organic chemistry to identify the critical attributes towards the development of sustainable pharmaceutical manufacturing routes and processes. As projects advance through development, pilot plant support may also be required across scales, culminating in the transfer of projects to our commercial manufacturing facilities around the globe.

Success in this role will require practical synthetic chemistry skills combined with a curious, inquisitive nature, and a passion for working in the laboratory in a safe manner while developing new scientific methodologies and learning new things. You will be working independently in the lab, being able to plan and execute your own workload and deliver high quality results.

At GSK we are committed to growing with our talent, and we will provide you the tools to own and design your development plan and pursue a career trajectory in the areas that interest you the most. Working at GSK offers opportunity to broaden your experience across R&D and our medicine supply chain.

This role will provide YOU the opportunity to lead key activities to progress YOUR career.  These responsibilities include some of the following:

• Designing and performing experiments in a laboratory setting to meet project timelines and objectives.
• Thinking creatively to generate new ideas for new synthetic routes and simplifying process problems.
• Ensuring that experimental work is communicated effectively at internal R&D meetings.
• Participating in technology transfer activities as appropriate to our manufacturing partners Pharma Supply Chain (PSC), other parts of R&D, and partner Contract Manufacturing Organisations (CMOs).
• Authoring or contributing to regulatory submissions, patents, scientific papers and other internal documentation relevant to the role.
• Complying with applicable Data Integrity, Quality, cGMP and regulatory requirements in all aspects of work.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• B.S. in Chemistry or scientific discipline with 2+ years of post-degree experience OR M.S. in Chemistry or scientific discipline
• Hands on synthetic organic chemistry experience (preferably in the pharmaceutical industry, or related sector)
• Experience in independent interpretation of data from experiments and using it to make meaningful conclusions/decisions regarding the direction of future experimentation

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Experience in multistep synthesis of organic molecules
• Experience with high throughput experimentation/automation for reaction optimization and process development activities
• Experience with Design of Experiments (DoE)
• Experience in implementation of basic kinetic characterization of organic reactions
• Excellent problem-solving skills
• Has the courage to take on ambitious goals and move forward at pace

Why GSK?

Our values and expectations are at the heart of everything we do and form an important part of of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

• Operating at pace and agile decision-making – using evidence and applying judgement to balance pace, rigour and risk.
• Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
• Continuously looking for opportunities to learn, build skills and share learning.
• Sustaining energy and well-being
• Building strong relationships and collaboration, honest and open conversations.
• Budgeting and cost-consciousness